Synchronous small-cell lung cancer and metastatic gastric gastrointestinal stromal tumor: concurrent chemo-radiotherapy, consolidation immunotherapy, and imatinib

Introduction Lung cancer is the most incident tumor in the world, with approximately 2.480.675 new cases annually and it is also the leading cause of cancer mortality, accounting for 1.817.469 deaths per year according to GLOBOCAN data.1 Data from the Spanish Group of Lung Cancer (GECP) Lung Cancer Observatory indicate that small-cell lung cancer (SCLC) […]

Tako-Tsubo syndrome after alectinib initiation

Introduction Anaplastic lymphoma kinase (ALK) inhibitors have revolutionized the treatment of ALK-positive non-small cell lung cancer (NSCLC), significantly improving survival and quality of life. Among second-generation ALK inhibitors, alectinib has been widely used due to its superior efficacy and safety profile compared to first-generation agents like crizotinib, as demonstrated in the phase III ALEX trial1 […]